Электронный научный журнал

All over the world, the proportion of elderly and senile people suffering from chronic non-infectious diseases is constantly increasing, and therefore the problem of comorbidity, the so-called “multimorbidity” in the domestic and world medical literature is currently receiving more and more attention. There is also rapid progress in the creation and introduction of a large number of medicines into practical healthcare.The desire to help the patient recover from all the diseases he has and to increase the effectiveness of treatment leads to the prescription of a large number of medications. Consequently, multimorbidity and associated polypharmacy are becoming an increasingly serious problem.Polypharmacy is associated with numerous negative clinical outcomes in older adults, such as frailty, hospitalization, increased falls, cognitive and physical impairment, and even mortality. This article reviews recent publications on the definitions, epidemiology, and clinical implications of polypharmacy.