The present study explores the possibility of employing the bilaterally represented system of finger dermatoglyphics as a model of structural organization of the brain two hemispheres. The very idea was based on the literature data on peculiarities of embryogenesis of hand skin pattern's formation as well as on genetic and phenotypic correlation between the brain motor functions and the finger dermatoglyphics. The indicators of bilateral asymmetry of finger dermatoglyphics were studied and compared in two groups of volunteers with the different type of hemispheres' dominance in organization of the brain motor function (“dominant” hand) and sensory function (“dominant" eye). The findings were indicative of statistically true difference in the bilateral asymmetry level between the right-handers and the left-handers, irrespective of the sensory asymmetry profile. The right-handers appeared to show more asymmetry in comparison with the left-handers. This trend is particularly manifested for the functionally active field of hand (Field R), involving I-III fingers.